Our website uses cookies please read our Privacy Policy. Please accept the use of cookies on our site.
Trending Products
001179 - Ethyl trifluoroacetate

CAS Number 383-63-1 MDL Number MFCD00000419
Boiling Point 60-62°C Melting Point
Density 1.194 Purity 99%
Molecular Formula C4H5F3O2 Molecular Weight 142.077
Add to Favourites
Stock and Pricing
Size Pack Price Stock Add
100g £ 10.00 > 10
500g £ 37.00 > 10
Request a Quote
Size Unit Qty Add
To view prices in your local currency and Order Online, please Log In to your account.

The lead times given for non-stock items are estimates based on historical data and available information. For fully accurate availability please enquire. When adding pack sizes please be aware shipping costs can be reduced by multiple quantities of pack sizes(Excepted and Limited Quantites).

Hazards and Precautions


Hazard Statements

H225: Highly flammable liquid and vapour.
H314: Causes severe skin burns and eye damage.
H319: Causes serious eye irritation.

Precautionary Statements

P210: Keep away from – No smoking.
P235: Keep cool.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof ./ equipment.
P242: Use only non-sparking tools.
P243: Take precautionary measures against static discharge.
P260: Do not breathe .
P264: Wash hands thoroughly after handling.
P280: Wear .
P301 + P330 + P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P321: Specific treatment (see . on this label).
P337 + P313: If eye irritation persists: Get medical advice/attention.
P363: Wash contaminated clothing before reuse.
P370 + P378: In case of fire: Use sand, CO2 or extinguishing powder for extinction.
P403 + P235: Store in a well-ventilated place. Keep cool.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.

Transport Hazards

UN Number 3272
Packing Group II
Shipping Name esters, n.o.s.
Sub Class
Limited Qty 1 L
Excepted Qty Inner(30g/mL)  Outer(500g/mL)
No Image

Search for Certificate of Analysis

Enter your lot number: 

Technical Information

Ethyl trifluoroacetate is a useful intermediate in the synthesis of pharmaceutical and agricultural chemicals. It is useful as a reagent for the mild N-trifluoroacetylation of amino acids and peptides1 and differentiating amino groups.2 It is also used for: Synthesis of trifluoromethyl ketones from Grignard reagents,3 Reaction with E-2-acetyl-2,3-diphenyloxirane to make 3-hydroxy-2,3-diphenyl-6-trifluoromethyl-2,3-dihydro-4H-pyran-4-one,4 and Synthesis of trifluoroacetyltrimethylsilane via its ethyltrimethylsilyl ketal.5

1. J. Org. Chem. 1979, 44, 2805.
2. Tetrahedron Lett. 1995, 36, 7357.
3. J. Org. Chem. 1987, 52, 5026.
4. Chem. Heterocycl. Compd. 200137, 540.
5. Tetrahedron Lett. 2003, 44, 3741.