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| CAS Number | 407-25-0 | MDL Number | MFCD00000416 |
|---|---|---|---|
| Boiling Point | 39.5-40°C | Melting Point | -65°C |
| Density | 1.487 | Purity | 99% |
| Molecular Formula | C4F6O3 | Molecular Weight | 210.031 |
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Stock and Pricing
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| Size | Pack | Price | Stock | Add |
|---|---|---|---|---|
| 100g | £ 10.00 | > 10 | ||
| 500g | £ 34.00 | > 10 | ||
| 1kg | £ 58.00 | > 10 |
| Size | Unit | Qty | Add |
|---|---|---|---|
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The lead times given for non-stock items are estimates based on historical data and available information. For fully accurate availability please enquire. When adding pack sizes please be aware shipping costs can be reduced by multiple quantities of pack sizes(Excepted and Limited Quantites).
Hazards and Precautions
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Hazard Statements
EUH014: Reacts violently with water.H314: Causes severe skin burns and eye damage.
H332: Harmful if inhaled.
H412: Harmful to aquatic life with long lasting effects.
Precautionary Statements
P260: Do not breathe .P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear .
P301 + P330 + P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see MSDS. on this label).
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local/regional/ national/international regulation.
Transport Hazards
| UN Number | 3265 |
|---|---|
| Packing Group | I |
| Shipping Name | corrosive liquid, acidic, organic, n.o.s. |
| Class |
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| Sub Class | |
| Limited Qty | Forbidden |
| Excepted Qty | Inner(Not Permitted) Outer(Not Permitted) |
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Technical Information
Abbreviated as TFAA. A reagent to introduce a trifluoromethyl group into an organic compounds. A trifluoroacetylating agent for protection of alcohols and amines, often used in trifluoacylation reactions like o-acylation, n-acylation or c-trifluoro-acylation.1 Applied as a catalyst in a smooth and efficient oxidation of isonitriles to isocyanates by sulfoxides,2 and for activating N,N'-di-Boc-substituted thiourea to thioacylate nucleophiles, such as amines, alcohols, thiols, sodium benzenethiolate, and sodium malonates.3 Also used in synthesis of [1,2,4]Triazolo[1,5- a]pyridines,4 oxidation of alkyl aryl ketones to α-hydroxyalkyl aryl ketones in good yield 5 and catalyzing a highly enantioselective rearrangement of β-amino alcohols.6
References
1. Tetrahedron 1987, 43, 5583.
2. Org. Lett. 2011, 13, 2584.
3. Synthesis 2010, 991.
4. J. Org. Chem. 2005, 70, 3761.
5. Synthesis, 2008, 3205.
6. J. Org. Chem., 2007, 72, 6556.
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