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035918 - N-Methyl-2-pyrrolidinone (Discontinued)

CAS Number 872-50-4 MDL Number MFCD00003193
Boiling Point 204.1°C Melting Point -24.2°
Density 1.03 Purity 99.8%
Molecular Formula C5H9NO Molecular Weight 99.133
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Hazards and Precautions


Hazard Statements

H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H360D: May damage the unborn child.

Precautionary Statements

P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P281: Use personal protective equipment as required.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .

None Hazardous for Transport

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Technical Information

A powerful, aprotic solvent with high solvency, and low volatility for use in numerous applications including graffiti removal, automotive and industrial cleaning, water borne coatings, and photoresist stripping. Used in the formulation for drugs by both oral and transdermal delivery routes.2 Also used as a dermal penetration enhancer for pharmaceuticals.3

1. Chromatographia 1997, 46, 141.
2. Water-Insoluble Drug Formulation, Edition 2,  2008.
3. Int. Arch. Occup. Environ. Health 2005, 78, 673.